Meet world's first test tube puppies

A team of veterinarians, scientists and lab workers gathered around a surrogate hound and watched her give birth to seven half-pound puppies, the first dogs ever conceived in a test tube.

"We each took a puppy and rubbed it with a little towel and when it started to squiggle and cry, we knew we had success," said Dr. Alexander Travis, who runs the lab at the Baker Institute for Animal Health at Cornell University's College of Veterinary Medicine in Ithaca, New York.

"Their eyes were closed. They were just adorable, cute, with smooshed-in faces. We checked them to make sure they looked normal and were all breathing," he said.

The puppies born July 10 are a mix of beagle, Labrador and cocker spaniel and are now healthy 5-month-olds, Travis said. All but one female were adopted. She's being kept by the lab to have her own litter.

The lab kept track of the puppies by painting their nails with different color polish. Travis adopted two, still known by their nail polish names, Red and Green.

In vitro fertilization, the process of fertilizing an egg with sperm outside the body, is widely used to assist human reproduction these days. The first human birth from IVF took place in 1978.

But IVF efforts with dogs repeatedly failed until now, according to Dr. Pierre Comizzoli, a reproductive physiologist for the Smithsonian Conservation Biology Institute in Front Royal, Virginia, which works with Cornell.

"The biology of the dog is really, really different than humans," Comizzoli said. Dog pregnancies last only two months and females go into heat just once or twice a year, releasing immature eggs instead of mature eggs needed for IVF.